SubtiBank SubtiBank
yhxC [2018-02-13T13:14:44.000Z]
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yhxC [2018-02-13T13:14:44.000Z]

similar to alcohol dehydrogenase
locus
BSU10400
pI
7.26
mw
30.69 kDa
protein length
285 aa Sequence Blast
gene length
855 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

    • Gene

    Coordinates
    1,115,698 → 1,116,555

    The protein

    Protein family

  • short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|3161519994609DA9360ED6E073E4A4C8C6210EFB|YdaD] (63%), [protein|EAEEA4DD9641919830A81185333A2610B964D37C|YhdF] (62.3%), [protein|739B228743BC1FE9E6888E999BC0E4F615E36F9E|YhxD] (45,2%),
  • [protein|0DD474462720CAEE2AE17017BD7CA385238EBC6F|YxbG] (36,2%), [protein|439B468A13137000FB42E9389391CB4986FFED84|FabG] (34.7%), [protein|B6FF689E65906186F3576B378650D713DB84EDDA|YcdF] (32,4%),
  • [protein|CA4597C6253CCF7D7954686A30AF041808BDF8E5|Gdh] (34,1%), [protein|20A7DBA142F3BF8DCAD9732BD908CE8CC79AA993|BacC] (36.0%), [protein|248F0805272FED9B38ECBB31E2872BC9EC163CE0|YmfI](30.3%), [protein|CE990D33A12C50D22506A52E0099F7D97A762D4E|FadH] (31.9%), [protein|FBBDE1E058223D5E8CEB07CAA50940A329C809E4|KduD](33,6%), [protein|4DEFC2998464BF8327578C36A13A10DD277F991E|YkvO] (35.2%), [protein|6BA346D8A7B496F9618AFAB4FEEF4BD1A41D2C7E|YoxD] (31,5%), [protein|D9D1FCBFC62F93CAA34DF61A784406F4E9EE6768|YjdA] (32,9%)

    • Structure

  • [PDB|3I30] (from ''Bacillus Anthracis Str. 'amesAncestor''', 68% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036|yhxC]
    description
    [Pubmed|8196543]

    sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|15699190,12480901], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]

    • regulation

  • expressed during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|15699190,12480901]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-A718 (yhxC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/718 NBRP B. subtilis, Japan]
  • BKE10400 (Δ[gene|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036|yhxC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE10400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGAAATCACTCCTTTTC, downstream forward: _UP4_TAATAAAAAGCCAATCCTTG
  • BKK10400 (Δ[gene|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036|yhxC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK10400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGAAATCACTCCTTTTC, downstream forward: _UP4_TAATAAAAAGCCAATCCTTG

    • References

  • 15699190,12480901,8196543